The objective of this article is to describe the use of lemon/lime juice for douching by female sex workers and family planning clients in Jos, Nigeria. Over half the women believed that it protected them from pregnancy and/or sexually transmitted infections; they did not know their HIV status. Eighty-six percent would recommend it to others, and 71% would be willing to take part in a study to evaluate its safety and efficacy. Conclusion: Lemon and lime juice are widely used for douches among women at high risk of HIV transmission.